Baptiste
Libé-Philippot
Baptiste Libé-Philippot is Group Leader at the IBDM (Marseille, France) since October 2024. He explores the evolution of human cerebellar neurons, from the molecular to the circuit to the behavioral levels, with the support of an ERC StG grant (hCerebEvol). His team “Human Neuronal Evolution” performs cross-species histological comparisons of neuronal morphology, synaptic innervation and gene expression across the cerebellar development, in human and other primate species, to identify human species-specific cellular features. To explore the underlying mechanisms and their functional impact, his team uses mouse gain-of-function models as well as loss-of-function approaches in human models. This project follows a postdoctoral training in the laboratory of Pierre Vanderhaeghen (CBD, Leuven, Belgium) in which he explored the evolutionary divergence of human cortical neurons (Libé-Philippot et al., Cell, 2023 & Neuron, 2024). This work was honoured by the Marc Hurard (Belgian Queen Elisabeth Medical Foundation) and Claude Paoletti (French CNRS) Awards.