Arthur Neuberger

Arthur
Neuberger

Walther Straub Institute of Pharmacology & Toxicology, Faculty of Medicine, LMU Munich, DE

Arthur Neuberger earned his PhD in pharmacology and biochemistry from the University of Cambridge in the UK in 2018, studying the structure and function of bacterial multidrug efflux pumps – bacterial cell membrane proteins/transporters that render bacterial cells resistant to a variety of antibiotics. As a DFG-funded Walter Benjamin Fellow, Dr. Neuberger has been pioneering research on the structure and function of mammalian TRP (Transient Receptor Potential) channels of the vanilloid subfamily. Whilst some TRP channels act as gate keepers or master regulators of ion homeostasis, other representatives of this diverse superfamily of ion channels act as direct molecular sensors for various cellular and environmental signals such as temperature. Neuberger mapped the first structure of human TRPV1, a key pain and heat sensor, providing an alternative to conventional opioid-based pain relief. Neuberger also discovered how plant compounds from cannabis and soy can block TRPV6, the major calcium uptake channel in the human gut and a channel heavily linked to various forms of human cancer. Arthur Neuberger’s work advanced our understanding of TRP channels and offered practical solutions for pain management, cancer treatments, and more. Since June 2024, Arthur Neuberger is Professor of Molecular BioImaging and Elite Network of Bavaria Group Leader at the Walther Straub Institute of Pharmacology & Toxicology at LMU Munich.

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