Andrew Luster

Andrew
Luster

Harvard Medical School & Massachusetts General Hospital, US

Andrew Luster is the Persis, Cyrus and Marlow B. Harrison Professor of Medicine at Harvard Medical School and the E. Alexandria and Michael N. Altman Chair in Immunology at Massachusetts General Hospital where he directs the research Center for Immunology & Inflammatory Diseases. Dr. Luster received his B.S. degree summa cum laude from Duke University, his Ph.D. from Rockefeller University, and his M.D. from Cornell University Medical College. Dr. Luster pursued his clinical training at Massachusetts General Hospital, followed by a post-doctoral fellowship in the Department of Genetics at Harvard Medical School.

Dr. Luster has been intimately associated with the development of the chemokine field. He has made multiple contributions to understanding the roles of this important family of immunoregulatory chemotactic cytokines in health and disease since his initial discovery of CXCL10 (IP-10). His laboratory has helped define how chemokines and lipid chemoattractants function in immune cell trafficking necessary to generate innate and adaptive immune responses in the host response to infectious pathogens and cancer, as well as in the pathogenesis of immune and inflammatory diseases, including autoimmune and allergic diseases, with a particular focus on allergic asthma. Areas of recent interest include the role of resident memory effector and regulatory T cells in regulating tissue immunity. One unifying principle under investigation is the role of specific chemokine systems in establishing tissue niches for the differentiation and maintenance of specific T cell populations in tissue, such as resident memory effector and regulatory T cells in tissue following allergic and autoimmune inflammation and infection.

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